Nanobiosystems, Medicine, and Health” and “Synthesis, Processing, and Manufacturing of Components, Devices, and Systems” to the world study on nanotechnology research directions for societal needs Nanotechnology Research Directions for Societal Needs in SmartFlares are a very minor part of the article. Beckman Young Investigators, — Retrieved 14 November Reference  correspond to six half a dozen articles, 80a to 80f see below for details and links.
Wrighton on microelectrode devices for electrocatalysis. I happen to agree with you that the flares lighting up in the endosome is a serious issue to be addressed and most certainly interferes with accurate detection of mRNA. Leave a Reply Cancel reply Enter your comment here Antisense gene regulation cannot happen without the particles going out of the endosomes. Let me refine those last sentences: Archived from the original on
He is the founding editor of the nanotechnology journal Smalland he is an associate editor of the Journal of the American Chemical Society. Retrieved 21 January pphd Retrieved 17 November Inhe was listed as the most cited chemist in the world over the last decade in terms of total citations, the second highest most cited chemist  in terms of impact factor,  and the top most cited phv researcher.
Retrieved 24 April But keep in mind that the same gene regulation effect can be seen with multivalent oligonucleotide nanoparticles of varying cores, such as self-assembled micellar structures, e.
Mirkin has pioneered kirkin use of DNA and nanoparticles as synthons in materials science and the development of nanoparticle -based biodiagnostics.
Archived thewis the original on 14 November These discoveries and innovations have led to over commercial products that are being used worldwide. Archived from the original on The author is a journalist working for the magazine, not a practicing scientist. It seems you are unfamiliar with the literature.
Email Address never made public. The mechanism of action of a drug does not need to be elucidated for it to be approved by the FDA, it just needs to be safe and effective.
Well, you said it yourself: Learn how your comment data is processed. Mirkin is known for his development of nanoparticle-based biodetection schemes, the invention of dip-pen nanolithography recognized by National Geographic as one of the top scientific discoveries that changed the worldand contributions to supramolecular chemistry, thrsis, and nanooptics.
They are being tested for antisense gene regulation, which has been demonstrated both in vivo and in vitro. I would say that reason is what is telling us that we should be concerned.
A RESPONSE FROM CHAD MIRKIN’S GROUP [follow up #1/n] | Rapha-z-lab
Like Liked by 1 person. Retrieved 7 May Retrieved from ” https: It assumes it does. In addition to his academic and research work, Mirkin has been involved in shaping science policy decisions. A common strategy used by Mirkin’s group is the use of the unique properties of spherical nucleic acids SNAsspherical arrangements of nucleic acids with or without organic or inorganic nanoparticle cores, to enable the synthesis of novel materials and colloidal crystals, the development of high sensitivity probes for chemical and medical diagnostic purposes, and single-entity structures capable of intracellular gene regulation.
Mine is not an indiscriminate bashing but a careful candid critique, based on published papers including their massive holesbasic knowledge of cell biology, as well as our own results: This site uses Akismet to reduce spam. Views Read Edit View history.
Some readers might wonder why I am going on about this, so let me tell you: Notify me of new comments via email. There may only be a couple mRNA copies in the cytosol that need to interact with a complementary oligo in order to observe knockdown.
Wilhelm Exner Medal; William H. Yes, your summary is pretty much what I was getting at.